Taken together, it is obvious that thanks to new and improved technologies aligner therapy is undergoing a radical change. From being regarded as a limited, premium-only solution, this module could quickly become the new standard for most orthodontic treatments. Considering the aesthetic nature and predictability of aligner treatments, the in-office/in-lab approach to aligners’ production may be the key in securing high-quality and affordable orthodontic corrections to larger-than-ever patient population.